The Unexpectedly Challenging, Yet Rewarding Life of Keanu Reeves

Initially, the Wachowskis preferred Johnny Depp for Neo in The Matrix, while Warner Bros. favored Brad Pitt or Val Kilmer. Ultimately, these first choices declined the offer, paving the way for another actor.

Despite finally agreeing on Depp, his hectic schedule forced him to reject the role. This led to Keanu Reeves becoming Neo, a now iconic role that imagining anyone else in his place seems unfathomable.